Despite winning many of the key statistical areas of their clash against the Raiders at Suncorp Stadium, Brisbane suffered a shock 20-14 loss which now has them just two points clear of the Panthers at the top of the ladder.
Kevin Walters' men will be eyeing an immediate return to winning ways in what is their third derby match in six weeks, following earlier victories over the Cowboys and Dolphins.
The Titans will have taken plenty of confidence from getting the job done against the Dragons in a 20-18 win.