This happened at Nine-Mile Makana, around 12am this morning, according to eyewitness Joseph Raiam.
Raiam and another two were on their way home when they saw the 5th element Ute speeding into town.
The driver, who was believed to be under the influence of alcohol, drove onto the wrong lane, heading straight into a 15 seater bus.
He says the driver of the 5th Element ran away, leaving behind the three injured passengers, believed to be from Milne Bay Province.
The three were assisted into a taxi and sent to the hospital.