Defending champions, the University of Papua New Guinea (UPNG) Pythons, will be defending their title this year, after winning the cup in a fiery grand final match against the University of Technology (Unitech) Spartans in Port Moresby, in 2021.
UPNG has assembled three teams; two from the main campus including defending champions, the UPNG Pythons. The Third UPNG Team is Medfac from the School of Medicine, Taurama campus.