Just three weeks ago Spurs sat top and Arsenal bottom after their worst start to a league season for 67 years.
However, the Gunners have been rejuvenated by six summer signings and the return to fitness of a number of key players.
Arsenal struck three times in the opening 35 minutes as Emile Smith Rowe opened the floodgates before Pierre-Emerick Aubameyang rounded off a brilliant team move and Bukayo Saka rolled home the third.
Son Heung-min pulled a goal back for the visitors 11 minutes from time, but it was too little, too late for Nuno Espirito Santo’s men.