The move will affect 14 dates in Asia and North America over the next three months.
Bieber has performed more than 150 shows since the tour promoting his 2015 album Purpose began in March 2016.
The tour grossed $93.2m (£71.5m) in the first half of 2017, with an average of almost 40,000 ticket sales per date.
The singer himself has not yet commented on the decision on social media, but unnamed sources told US media he was "just over it".
But a statement on his website read: "Justin loves his fans and hates to disappoint them.