Lizzie Velasquez is a motivational speaker who has given TED talks and has thousands of followers.
She was born with a rare, inherited condition which means her body is unable to store fat.
"I'm writing this post not as someone who is a victim but as someone who is using their voice.
"No matter what we look like or what size we are, at the end of the day we are all human," she wrote on Instagram.
As well as Lizzie, other memes feature plus-size women, older people and those with a disfigurement.