The 25-year-old, who returned to Old Trafford from Juventus for £89m in August 2016, has struggled to impress under Jose Mourinho this season and has been left out of the starting XI for United's last three games.
The midfielder is among those featured in the 25-man France squad for this month's friendlies against Colombia and Russia, but with the World Cup looming, Deschamps is concerned about the player.
"I don't know what it is. I'm sure I'll hear about it. Of course, it's a situation he won't be enjoying," he said.
