The round 5 women's division match was a tight first half but the Panthers managed a try to outside centre Katherine Anjo.
This gave them a 4-0 lead going into the break.
The second half of play was where the Panthers ravaged their opponents.
They struck twice on the same wing minutes from kick-off to extend the lead out to 14-0 lead.
The win was all but assured when Annie James scored out wide on the right wing.
In the other women's matches, Sisters beat Kone Storms 12-0 while the Dobo Warriors forfeited Tarangau.