The eight-try romp saw wing Tevita Li, fullback Patrick Osborne and his replacement Rob Thompson (two), flank Dillon Hunt and centre Richard Buckman also cross the line.
The Highlanders have now moved 10 points clear of the Blues in the fourth playoff spot in the New Zealand Conference after 12 matches, significantly boosting their chances of making the knockout stages.
The victory is the eighth in succession for the 2015 Super Rugby champions, who had started the campaign miserably with three defeats in their opening four games.