About 50,000 people were thought to have attended the concert, which comes 13 days after a suicide bombing hit Grande's show at Manchester arena, killing 22 people.
The concert at Old Trafford in Manchester City aims to support the families and victims affected by that attack.
Grande herself headlined the performance, and supporting acts include Justin Bieber, Coldplay, Katy Perry, Take That, Pharrell Williams, Niall Horan, Miley Cyrus, Usher, Robbie Williams, Little Mix and The Black Eyed Peas.