Allstate sank 10 percent Tuesday after its results came up far short of what analysts were expecting.
Drugmaker Baxalta surged 12 percent after Irish rival Shire offered to buy the company for $30 billion.
The Dow Jones industrial average fell 47 points, or 0.3 percent, to 17,550.
The Standard & Poor's 500 index gave up four points, or 0.2 percent, to 2,093.
