In an interview with GQ Magazine, the former wrestler turned actor says he has given the idea a lot of thought.
He says, "I feel that if I were president, poise would be important. Leadership would be important. Taking responsibility for everybody."
But Johnson's not the only star with their sights set on moving into the Whitehouse in 2021.
Mark Zuckerberg, the billionaire CEO of Facebook, may also be considering a career change.
He's been on a mission to visit people in all 50 US states and is broadcasting it all on Facebook Live, which could be seen as a bit of a PR push.
There's also been plenty more presidential photo ops, including riding on a tractor, feeding baby cows and even going to church in a suit instead of his famous black hoodie.
Jay Z may not have been able to help Hillary Clinton get the top job in US politics, but that doesn't mean he's ruling it out for himself.
An 'insider' apparently told Radar magazine, "Jay Z is really considering running for political office in New York and Beyonce is 1000 percent supportive of her husband's decision."
He even told Newsbeat back in 2010 he wished he was President.
If your dream is to see Kim Kardashian as First Lady, then you may have to wait a while.
That's because Kanye West has decided to wait until 2024 to run for President.
He previously announced he would run in 2020, but after meeting President Trump last year he decided he didn't want to oppose his potential second term.
In a now deleted Twitter rant, he said "Rappers are philosophers of our now, celebrities are the influencers of our now, just look at the president".
"[Trump] wasn't in politics and won."