Three days after helping Queensland win the Origin decider, Cherry-Evans was in fine touch at 4 Pines Park, helping Manly to score five unanswered tries in the final half hour and win for the sixth time in seven games at home this season.
The two sides traded converted tries through the opening 20 minutes, but Manly pulled away in the final 10 minutes of the half thanks to a Saab try and Cherry-Evans penalty.
Anthony Milford was sent to the bin just before the break for taking Reuben Garrick out off the ball.