After playing out a golden point thriller two months ago, the Panthers and Knights meet again after both suffering narrow losses in Round 16.
The Panthers on the other hand were the competition's hottest team prior to suffering defeat at the hands of the Cowboys in golden point last Friday, in what was their first loss since the end of April.
Penrith have had it all over the Knights in recent times and haven't lost to them in their past seven meetings, while stretching back to 2014 Newcastle have tasted victory over this week's opponent just twice in 16 meetings.