But how on Earth do these tiny creatures - with their minuscule brains - outwit us so easily?
You've probably pondered it after chasing a fly around your house and flailing your shoe with repeated, unsuccessful swats. How does it move so fast? Can it read my mind?
It was the question put to the BBC World Service CrowdScience team for our most recent episode addressing the apparent super powers of tiny animals. The answer is that, compared with you and me, flies essentially see the world in slow motion.